THE PRACTICE TEST
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A bacteria that prefers a neutral (pH 7) environment A type of coagulation factor in the blood A type of white blood cell A neutrophil is a type of white blood cell. It is the most common type of white blood cell in the body. Neutrophils engulf and destroy microbes through a process called phagocytosis.An atom with more neutrons than electrons
Leukocytosis Leukocytosis is an abnormally high level of white blood cells.Leukodystrophy Leukodystrophies are disorders affecting the white matter of the brain.Leukopenia Leukopenia is a low white blood cell count.Leukoplakia Leukoplakia is white patches in the mouth.
Common pathway Extrinsic pathway Intrinsic pathway The intrinsic pathway is also known as the contact activation pathway, because it is triggered by contact with certain surfaces, such as collagen.Tissue factor pathway Tissue factor pathway is another name for the extrinsic pathway. It is called the tissue factor pathway because it is activated by tissue factor, a protein released from damaged tissues.
Aldosterone Angiotensin II Angiotensin I is a biologically inactive precursor to angiotensin II. The angiotensin-converting enzyme (ACE) converts angiotensin I to angiotensin II. Angiotensin II exerts various effects on the body, including stimulating the release of vasopressin (antidiuretic hormone).Angiotensin III Renin
Albumin, fibrinogen, and globulin The major groups of proteins in plasma are albumin, fibrinogen, and globulin. Albumin is the most abundant plasma protein. It helps maintain osmotic pressure, transports substances, and regulates blood volume. Fibrinogen is a clotting factor. It converts into fibrin, forming a clot to stop bleeding. Globulins are a diverse group of proteins. There are three types of globulins: alpha, beta, and gamma. Alpha globulins transport lipids, fatty acids, and certain vitamins. Beta globulins transport iron and other substances. Gamma globulins, also known as antibodies, are used in immune responses.Albumin, globulin, and hemoglobin Fibrin, globulin, and albumin Insulin, glucagon, and hemoglobin
Clot formation phase Coagulation phase Hemostasis can be divided into four stages:- Vascular phase: Constriction of the blood vessel
- Platelet phase: Formation of a temporary “platelet plug"
- Coagulation phase: Activation of the coagulation cascade
- Clot formation: Formation of the “fibrin plug” or the final clot
Platelet phase Vascular phase
Factor VII Prothrombin Thrombin Tissue factor Damage to blood vessels releases tissue factor (also known as factor III). It binds with factor VII and calcium to form a complex that activates the extrinsic pathway of the coagulation cascade.
Blood coagulation Temporary blockage of a break by a platelet plug Vasoconstriction Hemostasis has three major steps:- vasoconstriction
- temporary blockage of a break by a platelet plug
- blood coagulation
Vasodilation
Factor X Fibrin During hemostasis, fibrin monomers polymerize (link together) to form long chains. These chains create a mesh that traps platelets and red blood cells, forming a blood clot that seals the wound.Plasmin Thrombin
Renin Secretin Serotonin Thrombin Factor IIa (also known as thrombin) cleaves fibrinogen into the fibrin monomers that form a fibrin clot.
Proteins in the blood Oncotic pressure is the osmotic pressure exerted by large molecules in the blood, mainly albumin.Proteins in the interstitial fluid Sodium and chloride ions in the blood The water component of the blood
Electrolytes Fibrinogen Plasma proteins White blood cells Formed elements are cells and cell fragments suspended in the plasma. The three classes of formed elements are red blood cells, white blood cells, and platelets.
Blood cells The formed elements are the cells in the blood. The three classes of formed elements are red blood cells, white blood cells, and platelets.Clotting factors Plasma proteins Serum antibodies
Fat Protein Starch Amylase is an enzyme that breaks down starch into disaccharides and trisaccharides. Other enzymes then convert these into glucose.Sugars
Basophils Erythrocytes Leukocytes Osteocytes Osteocytes are found in bone tissue.
Monocytes and eosinophils Monocytes and lymphocytes Neutrophils and basophils Neutrophils and lymphocytes Neutrophils and lymphocytes together make up around 92% of all white blood cells in adults.
Basophil Eosinophil Lymphocyte Neutrophil Neutrophils are the most common type of white blood cell in normal blood. They are easy to recognize on a blood smear because they usually have a segmented, multi-lobed nucleus, often with 3–5 lobes. Their cytoplasmic granules are usually pale and hard to see, so they may be described as inconspicuous.
Erythrocytes Hemoglobin Leukocytes Leukocytes, also known as white blood cells, protect the body from infection.Platelets
albumin Plasma is the liquid part of blood. It contains plasma proteins (albumin, globulin, and fibrinogen), clotting factors, electrolytes, antibodies, antigens, and hormones. Serum is the liquid portion that is left over when blood clots. It is similar to plasma but lacks fibrinogen and some clotting factors, which are used during clotting.fibrinogen Fibrinogen is found in plasma. Serum lacks fibrinogen because it is used up in the clotting process.platelets Plasma and serum do not contain platelets.red blood cells Plasma and serum do not contain red blood cells.
Eosinophils Erythrocytes The scientific name for red blood cells is erythrocytes. The word comes from erythro, meaning 'red', and cyte, meaning 'cell'.Monocytes Thrombocytes
To ensure hemostasis To provide immunity To stop bleeding by forming a clot over injuries To transport oxygen and carbon dioxide Red blood cells have two tasks: carrying oxygen and carrying carbon dioxide. They carry oxygen from the lungs to the body's tissues to ensure the tissues have enough oxygen. At the same time, they carry carbon dioxide to the lungs for removal from the body.
Albumin Globulins Hemoglobin Red blood cells are mostly made of hemoglobin (about 95% of their solid material is hemoglobin). They have no nucleus or organelles, which gives them extra space to carry hemoglobin.Mitochondria
B cells and T cells Lymphocytes are a type of immune cell. The two main types of lymphocytes are B cells and T cells. B cells make antibodies while T cells help kill tumor cells and control immune responses.Cytotoxic cells and helper cells Cytotoxic cells and helper cells are different functions of T cells.Granulocytes and agranulocytes Macrophages and thrombocytes
B cell Basophil Neutrophil Phagocytes are a type of white blood cell that ingest and destroy pathogens. They include monocytes, macrophages, neutrophils, and dendritic cells. White blood cells that are not phagocytes include lymphocytes (B cells, T cells, and natural killer cells), basophils, and eosinophils.T cell
Neutrophils are part of the adaptive immune system Neutrophils are part of the innate immune system Neutrophils are part of the innate immune system, which is the body's first line of defense against pathogens. Neutrophils capture and destroy invading microorganisms, through methods such as phagocytosis.Neutrophils contain hemoglobin Neutrophils do not have a nucleus
Basophil Eosinophil Erythrocyte Erythrocytes are red blood cells, not white blood cells.Neutrophil
Basophil Kupffer cell Macrophages are a type of white blood cell that engulf and digest pathogens. Kupffer cells are macrophages found in the liver. Other macrophages include alveolar macrophages (found in the lungs), microglia (found in the central nervous system), and histiocytes (found in connective tissue).Megakaryocyte T cell
Basophil Basophils are the rarest type of white blood cell, making up only 1% of the white blood cells in the blood.Lymphocyte Neutrophil Thrombocyte
Converting prothrombin to thrombin Forming a plug at sites of bleeding Platelets are blood cells that help in clotting by forming a plug in the holes of damaged blood vessels.Producing clotting factors Transporting oxygen
enzymes fats Lipase is an enzyme that breaks down fats into fatty acids and glycerol during digestion.proteins red blood cells
converts prothrombin to thrombin Prothrombinase converts prothrombin to thrombin, not vitamin K.destroys fibrin which allows a clot to dissolve gradually The enzyme plasmin breaks down fibrin and dissolves clots, not vitamin K.is essential for the liver's production of prothrombin Vitamin K is essential for the liver's production of prothrombin as well as several other proteins involved in blood clotting.is water soluble Vitamin K is fat-soluble, not water-soluble.
Plasma proteins Red blood cells Sweat White blood cells White blood cells are the preferred source of DNA samples. Red blood cells and plasma proteins do not contain DNA and therefore cannot be used for DNA testing. Sweat can contain DNA because it can contain shed cells, but white blood cells is the best answer.
Duffy Red blood cells lacking the Duffy antigen are relatively resistant to infection by Plasmodium vivax, the parasite that causes Plasmodium vivax malaria. The Duffy antigen is absent from the red blood cells of 90% of sub-Saharan Africans, conferring malaria resistance in this population.Kidd Lewis Rhesus
B− and AB− B− and A− B− and O− People with type B blood cannot receive any blood that has A antigens (i.e. type A or AB blood), because their immune system makes anti-A antibodies. If they receive blood with A antigens, it can cause a dangerous hemolytic reaction. Furthermore, Rh-negative patients are usually given Rh-negative red blood cells to avoid exposure to the D antigen and possible anti-D formation. So, a person with B− blood should receive B− or O− blood, which do not have A or D antigens.O− and O+
the antibodies circulating in their blood the antibodies on the surface of their red blood cells the antigens circulating in their blood the antigens on the surface of their red blood cells Blood group classification is based on the presence or absence of antigens on the surface of red blood cells. Blood group A has A antigens on the red blood cells, blood group B has B antigens on the red blood cells, blood group AB has both A and B antigens on the red blood cells, and blood group O has neither the A nor the B antigens on the red blood cells.
The antibodies in a pregnant woman's blood are destroying her baby's blood cells The person has a deficiency of Factor VIII, resulting in hemophilia The person has the D antigen on the surface of their red blood cells "Rhesus positive" means a person has the D antigen on the surface of their red blood cells. This antigen is part of the Rhesus (Rh) blood group system, which is significant for blood transfusions and pregnancy.The person has the rhesus antibody in their blood
A antigens and anti-A antibodies A antigens and anti-B antibodies B antigens and anti-A antibodies Blood group B individuals have B antigens on their red blood cells and anti-A antibodies in their bloodstream.B antigens and anti-B antibodies
Type A Type AB People with type AB blood can only donate red blood cells to other people with type AB blood. AB red blood cells have both A and B antigens, and recipients with type A, B, or O blood have anti-A and/or anti-B antibodies that attack these cells and cause a hemolytic transfusion reaction.Type B Type O
A+ AB+ People with AB+ blood are often called universal red blood cell recipients. Their plasma does not contain anti-A or anti-B antibodies, so they can receive red blood cells from any ABO group. Because they are RhD positive, they can also receive RhD-positive or RhD-negative red blood cells without forming anti-D.B+ O+
Agglutinins Antibodies Antigens The ABO blood group system is based on two antigens on red blood cells: the A antigen and the B antigen. The presence or absence of these antigens determines a person's ABO blood type.Immunoglobulins
A antigens People with type A blood have A antigens on their red blood cells.B antigens Anti-A antibodies Anti-B antibodies
Anti-A antibodies Anti-B antibodies In the ABO blood group system, people make antibodies against the antigens they do not have on their red blood cells. For example, a person with A antigens but no B antigens produces anti-B antibodies.Both anti-A and anti-B antibodies B antigens
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